Pediatric leukemia, a cancer of the white blood cells, can be treated in a variety of ways, but some patients do not respond to traditional treatments.
One British girl, diagnosed in May 2021, has had two cancer-free examinations at the end of 2022, thanks to a new, very specific treatment, that involved directly changing DNA.
The girl essentially had her T-cells replaced by edited T-cells from a donor. The donor cells were modified to remove CD7, a unique marker characteristic of T-cells, made immune to a chemotherapy drug, and edited to hunt any cells displaying CD7.
